Design of meningococcal factor H binding protein mutant vaccines that do not bind human complement factor H. [electronic resource]
Producer: 20121010Description: 2667-77 p. digitalISSN:- 1098-5522
- Amino Acid Sequence
- Amino Acid Substitution
- Animals
- Arginine
- Bacterial Proteins -- genetics
- Complement Factor H -- metabolism
- Gene Expression Regulation, Bacterial
- Humans
- Meningococcal Infections -- prevention & control
- Meningococcal Vaccines -- immunology
- Mice
- Models, Molecular
- Mutation
- Neisseria meningitidis -- genetics
- Protein Binding
- Protein Conformation
- Serine
- Vaccines, Synthetic -- immunology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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