Design of meningococcal factor H binding protein mutant vaccines that do not bind human complement factor H.

Pajon, Rolando

Design of meningococcal factor H binding protein mutant vaccines that do not bind human complement factor H. [electronic resource] - Infection and immunity Aug 2012 - 2667-77 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1098-5522

10.1128/IAI.00103-12 doi


Amino Acid Sequence
Amino Acid Substitution
Animals
Arginine
Bacterial Proteins--genetics
Complement Factor H--metabolism
Gene Expression Regulation, Bacterial
Humans
Meningococcal Infections--prevention & control
Meningococcal Vaccines--immunology
Mice
Models, Molecular
Mutation
Neisseria meningitidis--genetics
Protein Binding
Protein Conformation
Serine
Vaccines, Synthetic--immunology