Antitumor activity of MEK and PI3K inhibitors against malignant pleural mesothelioma cells in vitro and in vivo. [electronic resource]
Producer: 20121019Description: 449-56 p. digitalISSN:- 1791-2423
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Butadienes -- pharmacology
- Cell Proliferation -- drug effects
- Chromones -- pharmacology
- Drug Synergism
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Humans
- MAP Kinase Kinase Kinases -- antagonists & inhibitors
- MAP Kinase Signaling System -- drug effects
- Male
- Mesothelioma -- drug therapy
- Mice
- Mice, SCID
- Morpholines -- pharmacology
- Nitriles -- pharmacology
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoinositide-3 Kinase Inhibitors
- Pleural Neoplasms -- drug therapy
- Tumor Burden -- drug effects
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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