Beneficial effects of pioglitazone against cardiovascular injury are enhanced by combination with aliskiren in a rat model of diabetic nephropathy. [electronic resource]
Producer: 20120829Description: 862-71 p. digitalISSN:- 2042-7158
- Amides -- pharmacology
- Animals
- Antihypertensive Agents -- pharmacology
- Cardiomyopathies -- drug therapy
- Diabetic Nephropathies -- complications
- Disease Models, Animal
- Drug Therapy, Combination
- Fibrosis -- prevention & control
- Fumarates -- pharmacology
- Gene Expression Regulation -- drug effects
- Hypoglycemic Agents -- pharmacology
- Lipid Peroxidation -- drug effects
- Male
- Matrix Metalloproteinase 2 -- genetics
- Myocardium -- metabolism
- Nephrectomy
- Oxidative Stress -- drug effects
- Pioglitazone
- Rats
- Rats, Wistar
- Streptozocin
- Thiazolidinediones -- pharmacology
- Tissue Inhibitor of Metalloproteinase-2 -- genetics
- Transforming Growth Factor beta1 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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