Bench to bedside: elucidation of the OPG-RANK-RANKL pathway and the development of denosumab. [electronic resource]
Producer: 20120622Description: 401-19 p. digitalISSN:- 1474-1784
- Animals
- Antibodies, Monoclonal -- pharmacology
- Antibodies, Monoclonal, Humanized
- Bone Resorption -- physiopathology
- Bone and Bones -- metabolism
- Denosumab
- Drug Design
- Humans
- Osteoclasts -- physiology
- Osteoprotegerin -- metabolism
- RANK Ligand -- antagonists & inhibitors
- Receptor Activator of Nuclear Factor-kappa B -- metabolism
- Signal Transduction
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review
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