Binge-like ethanol consumption increases corticosterone levels and neurodegneration whereas occupancy of type II glucocorticoid receptors with mifepristone is neuroprotective. [electronic resource]
Producer: 20140818Description: 27-36 p. digitalISSN:- 1369-1600
- Adrenalectomy
- Alcohol-Induced Disorders, Nervous System -- etiology
- Alcoholic Intoxication -- metabolism
- Analysis of Variance
- Animals
- Binge Drinking -- complications
- Cholesterol -- administration & dosage
- Corticosterone -- administration & dosage
- Dentate Gyrus -- drug effects
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Drug Implants -- administration & dosage
- Entorhinal Cortex -- drug effects
- Ethanol -- administration & dosage
- Fluoresceins
- Hormone Antagonists -- administration & dosage
- Hypothalamo-Hypophyseal System -- drug effects
- Male
- Mifepristone -- administration & dosage
- Neuroprotective Agents
- Pituitary-Adrenal System -- drug effects
- Random Allocation
- Rats
- Rats, Sprague-Dawley
- Receptors, Glucocorticoid -- antagonists & inhibitors
- Silver Staining
- Stress, Physiological -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Intramural
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