Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathway. [electronic resource]
Producer: 20120823Description: C1731-40 p. digitalISSN:- 1522-1563
- Caco-2 Cells
- Cell Polarity
- Cell Proliferation
- Colon -- drug effects
- Complement Activation -- drug effects
- Complement C5a -- genetics
- Epithelial Cells -- drug effects
- Extracellular Signal-Regulated MAP Kinases -- antagonists & inhibitors
- HT29 Cells
- Humans
- Immunity, Innate
- Immunity, Mucosal
- Inflammation -- enzymology
- Interleukin-8 -- genetics
- Intestinal Absorption
- Intestinal Mucosa -- drug effects
- MAP Kinase Signaling System -- drug effects
- Permeability
- Phenotype
- Protein Kinase Inhibitors -- pharmacology
- RNA, Messenger -- metabolism
- Receptor, Anaphylatoxin C5a
- Receptors, Chemokine -- genetics
- Receptors, Complement -- genetics
- Time Factors
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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