A cytoplasmic tail determinant in HIV-1 Vpu mediates targeting of tetherin for endosomal degradation and counteracts interferon-induced restriction. [electronic resource]
Producer: 20120709Description: e1002609 p. digitalISSN:- 1553-7374
- Antigens, CD -- immunology
- Cytoplasm -- metabolism
- Endosomes -- metabolism
- GPI-Linked Proteins -- immunology
- Gene Expression Regulation, Viral
- HEK293 Cells -- metabolism
- HIV-1 -- drug effects
- HeLa Cells -- metabolism
- Human Immunodeficiency Virus Proteins -- genetics
- Humans
- Interferons -- pharmacology
- Jurkat Cells -- metabolism
- Protein Interaction Domains and Motifs -- physiology
- Protein Transport
- Viral Regulatory and Accessory Proteins -- genetics
- Virion -- metabolism
- Virus Assembly
- Virus Release -- drug effects
- Virus Replication
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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