Changes in intranuclear mobility of mature snRNPs provide a mechanism for splicing defects in spinal muscular atrophy. [electronic resource]
Producer: 20121220Description: 2626-37 p. digitalISSN:- 1477-9137
- Cell Nucleus -- drug effects
- Fatty Acids, Unsaturated -- pharmacology
- Fibroblasts -- drug effects
- HeLa Cells
- Humans
- Models, Biological
- Muscular Atrophy, Spinal -- genetics
- Protein Transport -- drug effects
- RNA Interference -- drug effects
- RNA Splicing -- drug effects
- RNA, Small Interfering -- metabolism
- Ribonucleoprotein, U1 Small Nuclear -- metabolism
- Ribonucleoproteins, Small Nuclear -- metabolism
- Spliceosomes -- drug effects
- Survival of Motor Neuron 1 Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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