Clarifying the importance of CYP2C19 and PON1 in the mechanism of clopidogrel bioactivation and in vivo antiplatelet response. [electronic resource]
Producer: 20130429Description: 2856-2464a p. digitalISSN:- 1522-9645
- Adolescent
- Adult
- Area Under Curve
- Aryl Hydrocarbon Hydroxylases -- genetics
- Aryldialkylphosphatase -- genetics
- Biotransformation -- drug effects
- Clopidogrel
- Cytochrome P-450 CYP2C19
- Cytochrome P-450 CYP3A -- drug effects
- Enzyme Inhibitors -- pharmacokinetics
- Humans
- Midazolam -- pharmacokinetics
- Middle Aged
- Platelet Aggregation -- drug effects
- Platelet Aggregation Inhibitors -- pharmacokinetics
- Polymorphism, Genetic -- genetics
- Ticlopidine -- analogs & derivatives
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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