A small molecule modulator of prion protein increases human mesenchymal stem cell lifespan, ex vivo expansion, and engraftment to bone marrow in NOD/SCID mice. [electronic resource]
Producer: 20121129Description: 1134-43 p. digitalISSN:- 1549-4918
- Animals
- Bone Marrow Cells -- cytology
- Cell Differentiation -- physiology
- Cell Growth Processes -- physiology
- Cells, Cultured
- Gene Knockdown Techniques
- HEK293 Cells
- Humans
- Lentivirus -- genetics
- Mesenchymal Stem Cell Transplantation -- methods
- Mesenchymal Stem Cells -- cytology
- Mice
- Mice, Inbred NOD
- Mice, SCID
- Phosphorylation
- Prions -- biosynthesis
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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