A small molecule modulator of prion protein increases human mesenchymal stem cell lifespan, ex vivo expansion, and engraftment to bone marrow in NOD/SCID mice.
Mohanty, Sindhu T
A small molecule modulator of prion protein increases human mesenchymal stem cell lifespan, ex vivo expansion, and engraftment to bone marrow in NOD/SCID mice. [electronic resource] - Stem cells (Dayton, Ohio) Jun 2012 - 1134-43 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1549-4918
10.1002/stem.1065 doi
Animals
Bone Marrow Cells--cytology
Cell Differentiation--physiology
Cell Growth Processes--physiology
Cells, Cultured
Gene Knockdown Techniques
HEK293 Cells
Humans
Lentivirus--genetics
Mesenchymal Stem Cell Transplantation--methods
Mesenchymal Stem Cells--cytology
Mice
Mice, Inbred NOD
Mice, SCID
Phosphorylation
Prions--biosynthesis
Transfection
A small molecule modulator of prion protein increases human mesenchymal stem cell lifespan, ex vivo expansion, and engraftment to bone marrow in NOD/SCID mice. [electronic resource] - Stem cells (Dayton, Ohio) Jun 2012 - 1134-43 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1549-4918
10.1002/stem.1065 doi
Animals
Bone Marrow Cells--cytology
Cell Differentiation--physiology
Cell Growth Processes--physiology
Cells, Cultured
Gene Knockdown Techniques
HEK293 Cells
Humans
Lentivirus--genetics
Mesenchymal Stem Cell Transplantation--methods
Mesenchymal Stem Cells--cytology
Mice
Mice, Inbred NOD
Mice, SCID
Phosphorylation
Prions--biosynthesis
Transfection