Fucoxanthin attenuates rifampin-induced cytochrome P450 3A4 (CYP3A4) and multiple drug resistance 1 (MDR1) gene expression through pregnane X receptor (PXR)-mediated pathways in human hepatoma HepG2 and colon adenocarcinoma LS174T cells. [electronic resource]
Producer: 20120629Description: 242-257 p. digitalISSN:- 1660-3397
- ATP Binding Cassette Transporter, Subfamily B
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- genetics
- Adenocarcinoma -- drug therapy
- Cell Line, Tumor
- Colonic Neoplasms -- drug therapy
- Constitutive Androstane Receptor
- Cytochrome P-450 CYP3A -- genetics
- Hep G2 Cells
- Humans
- Pregnane X Receptor
- Promoter Regions, Genetic
- RNA, Messenger -- analysis
- Receptors, Cytoplasmic and Nuclear -- physiology
- Receptors, Steroid -- antagonists & inhibitors
- Rifampin -- pharmacology
- Transcriptional Activation
- Xanthophylls -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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