Sorafenib sensitizes human colorectal carcinoma to radiation via suppression of NF-κB expression in vitro and in vivo. [electronic resource]
Producer: 20120605Description: 12-20 p. digitalISSN:- 1950-6007
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Benzenesulfonates -- pharmacology
- Blotting, Western
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Colorectal Neoplasms -- drug therapy
- Combined Modality Therapy
- Electrophoretic Mobility Shift Assay
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Male
- Mice
- Mice, SCID
- NF-kappa B -- drug effects
- Niacinamide -- analogs & derivatives
- Phenylurea Compounds
- Pyridines -- pharmacology
- Radiation-Sensitizing Agents -- pharmacology
- Sorafenib
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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