Sorafenib sensitizes human colorectal carcinoma to radiation via suppression of NF-κB expression in vitro and in vivo.
Kuo, Yu-Cheng
Sorafenib sensitizes human colorectal carcinoma to radiation via suppression of NF-κB expression in vitro and in vivo. [electronic resource] - Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Feb 2012 - 12-20 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1950-6007
10.1016/j.biopha.2011.09.011 doi
Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Benzenesulfonates--pharmacology
Blotting, Western
Cell Cycle--drug effects
Cell Line, Tumor
Colorectal Neoplasms--drug therapy
Combined Modality Therapy
Electrophoretic Mobility Shift Assay
Gene Expression Regulation, Neoplastic--drug effects
Humans
Male
Mice
Mice, SCID
NF-kappa B--drug effects
Niacinamide--analogs & derivatives
Phenylurea Compounds
Pyridines--pharmacology
Radiation-Sensitizing Agents--pharmacology
Sorafenib
Xenograft Model Antitumor Assays
Sorafenib sensitizes human colorectal carcinoma to radiation via suppression of NF-κB expression in vitro and in vivo. [electronic resource] - Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Feb 2012 - 12-20 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1950-6007
10.1016/j.biopha.2011.09.011 doi
Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Benzenesulfonates--pharmacology
Blotting, Western
Cell Cycle--drug effects
Cell Line, Tumor
Colorectal Neoplasms--drug therapy
Combined Modality Therapy
Electrophoretic Mobility Shift Assay
Gene Expression Regulation, Neoplastic--drug effects
Humans
Male
Mice
Mice, SCID
NF-kappa B--drug effects
Niacinamide--analogs & derivatives
Phenylurea Compounds
Pyridines--pharmacology
Radiation-Sensitizing Agents--pharmacology
Sorafenib
Xenograft Model Antitumor Assays