Suppression of matrix metalloproteinase-9 expression by andrographolide in human monocytic THP-1 cells via inhibition of NF-κB activation. [electronic resource]
Producer: 20120529Description: 270-7 p. digitalISSN:- 1618-095X
- Andrographis -- chemistry
- Cell Line
- Cell Survival
- Diterpenes -- pharmacology
- Dose-Response Relationship, Drug
- Electrophoretic Mobility Shift Assay
- Enzyme Activation -- drug effects
- Enzyme-Linked Immunosorbent Assay
- Genes, Reporter
- Humans
- I-kappa B Proteins -- metabolism
- Lipopolysaccharides -- adverse effects
- MAP Kinase Signaling System
- Matrix Metalloproteinase 9 -- genetics
- Matrix Metalloproteinase Inhibitors
- Monocytes -- drug effects
- NF-KappaB Inhibitor alpha
- NF-kappa B -- antagonists & inhibitors
- Protease Inhibitors -- pharmacology
- Protein Transport
- Proteolysis -- drug effects
- RNA, Messenger -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Tissue Inhibitor of Metalloproteinase-1 -- metabolism
- Transcriptional Activation -- drug effects
- Transfection
- Tumor Necrosis Factor-alpha -- adverse effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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