Suppression of matrix metalloproteinase-9 expression by andrographolide in human monocytic THP-1 cells via inhibition of NF-κB activation.
Lee, Woan-Ruoh
Suppression of matrix metalloproteinase-9 expression by andrographolide in human monocytic THP-1 cells via inhibition of NF-κB activation. [electronic resource] - Phytomedicine : international journal of phytotherapy and phytopharmacology Feb 2012 - 270-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1618-095X
10.1016/j.phymed.2011.11.012 doi
Andrographis--chemistry
Cell Line
Cell Survival
Diterpenes--pharmacology
Dose-Response Relationship, Drug
Electrophoretic Mobility Shift Assay
Enzyme Activation--drug effects
Enzyme-Linked Immunosorbent Assay
Genes, Reporter
Humans
I-kappa B Proteins--metabolism
Lipopolysaccharides--adverse effects
MAP Kinase Signaling System
Matrix Metalloproteinase 9--genetics
Matrix Metalloproteinase Inhibitors
Monocytes--drug effects
NF-KappaB Inhibitor alpha
NF-kappa B--antagonists & inhibitors
Protease Inhibitors--pharmacology
Protein Transport
Proteolysis--drug effects
RNA, Messenger--metabolism
Reverse Transcriptase Polymerase Chain Reaction
Tissue Inhibitor of Metalloproteinase-1--metabolism
Transcriptional Activation--drug effects
Transfection
Tumor Necrosis Factor-alpha--adverse effects
Suppression of matrix metalloproteinase-9 expression by andrographolide in human monocytic THP-1 cells via inhibition of NF-κB activation. [electronic resource] - Phytomedicine : international journal of phytotherapy and phytopharmacology Feb 2012 - 270-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1618-095X
10.1016/j.phymed.2011.11.012 doi
Andrographis--chemistry
Cell Line
Cell Survival
Diterpenes--pharmacology
Dose-Response Relationship, Drug
Electrophoretic Mobility Shift Assay
Enzyme Activation--drug effects
Enzyme-Linked Immunosorbent Assay
Genes, Reporter
Humans
I-kappa B Proteins--metabolism
Lipopolysaccharides--adverse effects
MAP Kinase Signaling System
Matrix Metalloproteinase 9--genetics
Matrix Metalloproteinase Inhibitors
Monocytes--drug effects
NF-KappaB Inhibitor alpha
NF-kappa B--antagonists & inhibitors
Protease Inhibitors--pharmacology
Protein Transport
Proteolysis--drug effects
RNA, Messenger--metabolism
Reverse Transcriptase Polymerase Chain Reaction
Tissue Inhibitor of Metalloproteinase-1--metabolism
Transcriptional Activation--drug effects
Transfection
Tumor Necrosis Factor-alpha--adverse effects