Physicochemical and pharmacokinetic characterization of amorphous solid dispersion of tranilast with enhanced solubility in gastric fluid and improved oral bioavailability. [electronic resource]
Producer: 20130603Description: 379-87 p. digitalISSN:- 1880-0920
- Administration, Oral
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- administration & dosage
- Area Under Curve
- Biological Availability
- Calorimetry, Differential Scanning
- Chemistry, Pharmaceutical
- Chromatography, Liquid
- Crystallization
- Crystallography, X-Ray
- Drug Stability
- Gastric Juice -- chemistry
- Hydrogen-Ion Concentration
- Hydrophobic and Hydrophilic Interactions
- Injections, Intravenous
- Male
- Metabolic Clearance Rate
- Microscopy, Electron, Scanning
- Microscopy, Polarization
- Models, Biological
- Polymethacrylic Acids -- chemistry
- Powder Diffraction
- Rats
- Rats, Sprague-Dawley
- Solubility
- Spectrometry, Mass, Electrospray Ionization
- Spectroscopy, Fourier Transform Infrared
- Spectroscopy, Near-Infrared
- Technology, Pharmaceutical -- methods
- ortho-Aminobenzoates -- administration & dosage
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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