Widdrol activates DNA damage checkpoint through the signaling Chk2-p53-Cdc25A-p21-MCM4 pathway in HT29 cells. [electronic resource]
Producer: 20120702Description: 281-9 p. digitalISSN:- 1573-4919
- Adenocarcinoma -- enzymology
- Animals
- Antineoplastic Agents, Phytogenic -- pharmacology
- Apoptosis -- drug effects
- Benzocycloheptenes -- pharmacology
- Cell Cycle Proteins -- metabolism
- Checkpoint Kinase 2
- Colonic Neoplasms -- enzymology
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- DNA Breaks, Double-Stranded
- DNA-Binding Proteins -- metabolism
- Fibroblasts -- drug effects
- G1 Phase Cell Cycle Checkpoints -- drug effects
- HT29 Cells
- Histones -- metabolism
- Humans
- Mice
- Minichromosome Maintenance Complex Component 4
- Nuclear Proteins -- metabolism
- Phosphorylation
- Protein Serine-Threonine Kinases -- metabolism
- Signal Transduction -- drug effects
- Time Factors
- Tumor Suppressor Protein p53 -- metabolism
- cdc25 Phosphatases -- metabolism
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.