Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human. [electronic resource]
Producer: 20120927Description: 67-86 p. digitalISSN:- 1573-8744
- Adalimumab
- Algorithms
- Animal Structures -- metabolism
- Animals
- Antibodies, Monoclonal -- blood
- Antibodies, Monoclonal, Humanized -- blood
- Antigens, Neoplasm -- immunology
- Area Under Curve
- Blood -- metabolism
- Drug Evaluation, Preclinical -- methods
- Endosomes -- metabolism
- Extracellular Space -- metabolism
- Haplorhini
- Histocompatibility Antigens Class I -- genetics
- Humans
- Immunoglobulins, Intravenous -- administration & dosage
- Lymph -- metabolism
- Male
- Mice
- Mice, Knockout
- Models, Biological
- Neoplasms -- immunology
- Pinocytosis -- physiology
- Rats
- Receptors, Fc -- genetics
- Tissue Distribution -- drug effects
- Xenograft Model Antitumor Assays
No physical items for this record
Publication Type: Journal Article
There are no comments on this title.
Log in to your account to post a comment.