Activation of mTOR by human T-cell leukemia virus type 1 Tax is important for the transformation of mouse T cells to interleukin-2-independent growth. [electronic resource]
Producer: 20120325Description: 369-74 p. digitalISSN:- 1349-7006
- Animals
- Cell Line
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Transformation, Viral
- Gene Products, tax -- genetics
- Human T-lymphotropic virus 1
- Humans
- Interleukin-2 -- metabolism
- Mice
- Mutation
- Oncogene Protein v-akt -- metabolism
- Phosphorylation
- Ribosomal Protein S6 Kinases, 70-kDa -- metabolism
- Sirolimus -- pharmacology
- T-Lymphocytes -- physiology
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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