Activation of mTOR by human T-cell leukemia virus type 1 Tax is important for the transformation of mouse T cells to interleukin-2-independent growth.

Yoshita, Manami

Activation of mTOR by human T-cell leukemia virus type 1 Tax is important for the transformation of mouse T cells to interleukin-2-independent growth. [electronic resource] - Cancer science Feb 2012 - 369-74 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1349-7006

10.1111/j.1349-7006.2011.02123.x doi


Animals
Cell Line
Cell Line, Tumor
Cell Proliferation--drug effects
Cell Transformation, Viral
Gene Products, tax--genetics
Human T-lymphotropic virus 1
Humans
Interleukin-2--metabolism
Mice
Mutation
Oncogene Protein v-akt--metabolism
Phosphorylation
Ribosomal Protein S6 Kinases, 70-kDa--metabolism
Sirolimus--pharmacology
T-Lymphocytes--physiology
TOR Serine-Threonine Kinases--antagonists & inhibitors