Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibition. [electronic resource]
Producer: 20111206Description: 14600-10 p. digitalISSN:- 1529-2401
- Analysis of Variance
- Animals
- Animals, Newborn
- Arachidonic Acids -- pharmacology
- Benzoxazines -- pharmacology
- Benzoxazoles -- pharmacology
- Biphenyl Compounds -- pharmacology
- Calcium Channel Blockers
- Cannabinoid Receptor Modulators -- pharmacology
- Disease Models, Animal
- Electric Stimulation
- Endocannabinoids
- Enzyme Inhibitors -- pharmacology
- Estrenes -- pharmacology
- Glycerides -- pharmacology
- In Vitro Techniques
- Inhibitory Postsynaptic Potentials -- drug effects
- Intracellular Signaling Peptides and Proteins -- metabolism
- Lactones -- pharmacology
- Male
- Morpholines -- pharmacology
- Naphthalenes -- pharmacology
- Naphthyridines
- Neural Inhibition -- drug effects
- Neural Pathways -- drug effects
- Neuropeptides -- metabolism
- Orexin Receptors
- Orexins
- Orlistat
- Pain -- drug therapy
- Pain Measurement -- drug effects
- Patch-Clamp Techniques
- Periaqueductal Gray -- drug effects
- Piperidines -- pharmacology
- Pyrazoles -- pharmacology
- Pyrrolidinones -- pharmacology
- Rats
- Rats, Wistar
- Receptors, G-Protein-Coupled -- antagonists & inhibitors
- Receptors, Neuropeptide -- antagonists & inhibitors
- Urea -- analogs & derivatives
- gamma-Aminobutyric Acid -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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