Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibition.

Ho, Yu-Cheng

Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibition. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Oct 2011 - 14600-10 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1529-2401

10.1523/JNEUROSCI.2671-11.2011 doi


Analysis of Variance
Animals
Animals, Newborn
Arachidonic Acids--pharmacology
Benzoxazines--pharmacology
Benzoxazoles--pharmacology
Biphenyl Compounds--pharmacology
Calcium Channel Blockers
Cannabinoid Receptor Modulators--pharmacology
Disease Models, Animal
Electric Stimulation
Endocannabinoids
Enzyme Inhibitors--pharmacology
Estrenes--pharmacology
Glycerides--pharmacology
In Vitro Techniques
Inhibitory Postsynaptic Potentials--drug effects
Intracellular Signaling Peptides and Proteins--metabolism
Lactones--pharmacology
Male
Morpholines--pharmacology
Naphthalenes--pharmacology
Naphthyridines
Neural Inhibition--drug effects
Neural Pathways--drug effects
Neuropeptides--metabolism
Orexin Receptors
Orexins
Orlistat
Pain--drug therapy
Pain Measurement--drug effects
Patch-Clamp Techniques
Periaqueductal Gray--drug effects
Piperidines--pharmacology
Pyrazoles--pharmacology
Pyrrolidinones--pharmacology
Rats
Rats, Wistar
Receptors, G-Protein-Coupled--antagonists & inhibitors
Receptors, Neuropeptide--antagonists & inhibitors
Urea--analogs & derivatives
gamma-Aminobutyric Acid--metabolism