Decreased catalytic function with altered sumoylation of DNA topoisomerase I in the nuclei of scleroderma fibroblasts. [electronic resource]
Producer: 20120329Description: R128 p. digitalISSN:- 1478-6362
- Biocatalysis
- Blotting, Western
- Cell Nucleus -- enzymology
- DNA Topoisomerases, Type I -- metabolism
- Female
- Fibroblasts -- enzymology
- Humans
- Immunohistochemistry
- Immunoprecipitation
- Male
- RNA, Small Interfering
- Real-Time Polymerase Chain Reaction
- Reverse Transcriptase Polymerase Chain Reaction
- Scleroderma, Systemic -- enzymology
- Sumoylation
- Transfection
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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