CaMKII-dependent SR Ca leak contributes to doxorubicin-induced impaired Ca handling in isolated cardiac myocytes. [electronic resource]
Producer: 20120127Description: 749-59 p. digitalISSN:- 1095-8584
- Action Potentials -- drug effects
- Animals
- Benzylamines -- pharmacology
- Blotting, Western
- Calcium -- metabolism
- Calcium-Calmodulin-Dependent Protein Kinase Type 2 -- antagonists & inhibitors
- Diastole
- Doxorubicin -- adverse effects
- Free Radical Scavengers -- pharmacology
- Gene Expression
- Ion Transport -- drug effects
- Isoenzymes -- antagonists & inhibitors
- Melatonin -- pharmacology
- Mice
- Microscopy, Fluorescence
- Myocardial Contraction -- drug effects
- Myocytes, Cardiac -- cytology
- Phosphorylation
- Protein Kinase Inhibitors -- pharmacology
- Rats
- Rats, Wistar
- Reactive Oxygen Species -- antagonists & inhibitors
- Sarcoplasmic Reticulum -- drug effects
- Sulfonamides -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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