Setting up a kinase discovery and development project. [electronic resource]
Producer: 20140815Description: 3-18 p. digitalISSN:- 0070-217X
- Adenosine Triphosphate -- chemistry
- Animals
- Crystallography, X-Ray
- Drug Discovery -- methods
- Drug Evaluation, Preclinical -- methods
- Drug-Related Side Effects and Adverse Reactions
- Enzyme Activation
- Enzyme Assays -- methods
- Humans
- Indoles -- pharmacology
- Melanoma -- drug therapy
- Mice
- Niacinamide -- analogs & derivatives
- Phenylurea Compounds -- chemistry
- Phosphorylation
- Protein Kinase Inhibitors -- chemistry
- Solubility
- Sorafenib
- Structure-Activity Relationship
- Sulfonamides -- pharmacology
- raf Kinases -- antagonists & inhibitors
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Publication Type: Journal Article
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