Setting up a kinase discovery and development project.

Bollag, Gideon

Setting up a kinase discovery and development project. [electronic resource] - Current topics in microbiology and immunology 2012 - 3-18 p. digital

Publication Type: Journal Article

0070-217X

10.1007/82_2011_159 doi


Adenosine Triphosphate--chemistry
Animals
Crystallography, X-Ray
Drug Discovery--methods
Drug Evaluation, Preclinical--methods
Drug-Related Side Effects and Adverse Reactions
Enzyme Activation
Enzyme Assays--methods
Humans
Indoles--pharmacology
Melanoma--drug therapy
Mice
Niacinamide--analogs & derivatives
Phenylurea Compounds--chemistry
Phosphorylation
Protein Kinase Inhibitors--chemistry
Solubility
Sorafenib
Structure-Activity Relationship
Sulfonamides--pharmacology
raf Kinases--antagonists & inhibitors