The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans. [electronic resource]
Producer: 20111031Description: 3635-44 p. digitalISSN:- 1558-8238
- Alleles
- Autoantibodies -- immunology
- Autoimmune Diseases -- genetics
- Autoimmunity -- immunology
- B-Lymphocytes -- cytology
- Genetic Predisposition to Disease
- Humans
- Isoenzymes -- genetics
- Polymorphism, Single Nucleotide
- Protein Tyrosine Phosphatase, Non-Receptor Type 22 -- genetics
- Risk Factors
- Self Tolerance -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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