The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans.
Menard, Laurence
The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans. [electronic resource] - The Journal of clinical investigation Sep 2011 - 3635-44 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1558-8238
10.1172/JCI45790 doi
Alleles
Autoantibodies--immunology
Autoimmune Diseases--genetics
Autoimmunity--immunology
B-Lymphocytes--cytology
Genetic Predisposition to Disease
Humans
Isoenzymes--genetics
Polymorphism, Single Nucleotide
Protein Tyrosine Phosphatase, Non-Receptor Type 22--genetics
Risk Factors
Self Tolerance--genetics
The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans. [electronic resource] - The Journal of clinical investigation Sep 2011 - 3635-44 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1558-8238
10.1172/JCI45790 doi
Alleles
Autoantibodies--immunology
Autoimmune Diseases--genetics
Autoimmunity--immunology
B-Lymphocytes--cytology
Genetic Predisposition to Disease
Humans
Isoenzymes--genetics
Polymorphism, Single Nucleotide
Protein Tyrosine Phosphatase, Non-Receptor Type 22--genetics
Risk Factors
Self Tolerance--genetics