Cathepsin S is activated during colitis and causes visceral hyperalgesia by a PAR2-dependent mechanism in mice. [electronic resource]
Producer: 20120120Description: 1864-74.e1-3 p. digitalISSN:- 1528-0012
- Animals
- Cathepsin B -- metabolism
- Cathepsin L -- metabolism
- Cathepsins -- metabolism
- Colitis -- chemically induced
- Colon -- metabolism
- Crohn Disease
- Disease Models, Animal
- Gene Deletion
- Hyperalgesia -- etiology
- Interleukin-10 -- genetics
- Macrophages -- metabolism
- Magnetic Resonance Imaging
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Nociceptors -- metabolism
- Piroxicam -- adverse effects
- Receptor, PAR-2 -- genetics
- Signal Transduction -- physiology
- Visceral Pain -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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