Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells. [electronic resource]
Producer: 20111123Description: 6061-72 p. digitalISSN:- 1538-7445
- AC133 Antigen
- Adaptor Proteins, Signal Transducing
- Animals
- Antigens, CD -- metabolism
- Brain Neoplasms -- metabolism
- Calcium-Binding Proteins -- biosynthesis
- Cell Growth Processes -- physiology
- Endothelial Cells -- metabolism
- Gene Knockdown Techniques
- Glioblastoma -- metabolism
- Glycoproteins -- metabolism
- Humans
- Intercellular Signaling Peptides and Proteins -- biosynthesis
- Intermediate Filament Proteins -- metabolism
- Membrane Proteins -- biosynthesis
- Mice
- Neoplastic Stem Cells -- metabolism
- Nerve Tissue Proteins -- metabolism
- Nestin
- Peptides -- metabolism
- RNA, Small Interfering -- administration & dosage
- Receptors, Notch -- biosynthesis
- Serrate-Jagged Proteins
- Stem Cell Niche
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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