Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. [electronic resource]
Producer: 20110928Description: 346-50 p. digitalISSN:- 1476-4687
- Animals
- Biomarkers, Tumor -- metabolism
- Breast Neoplasms -- enzymology
- Cell Line, Tumor
- Cell Proliferation
- Citric Acid Cycle -- physiology
- Gene Expression Regulation, Enzymologic
- Gene Expression Regulation, Neoplastic
- Genomics
- Glutamic Acid -- metabolism
- Humans
- Ketoglutaric Acids -- metabolism
- Melanoma -- enzymology
- Mice
- Neoplasm Transplantation
- Phosphoglycerate Dehydrogenase -- genetics
- RNA Interference
- Serine -- biosynthesis
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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