Pentoxifylline aggravates fatty liver in obese and diabetic ob/ob mice by increasing intestinal glucose absorption and activating hepatic lipogenesis. [electronic resource]
Producer: 20120907Description: 1361-74 p. digitalISSN:- 1476-5381
- Adipocytes -- drug effects
- Animals
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
- Biomarkers -- blood
- Blood Glucose -- drug effects
- Cell Line, Tumor
- Diabetes Mellitus, Type 2 -- genetics
- Fatty Liver -- genetics
- Glucose -- genetics
- Glucose Tolerance Test -- methods
- Glucose Transporter Type 2 -- genetics
- Glycolysis -- drug effects
- Humans
- Inflammation -- genetics
- Intestinal Absorption -- drug effects
- Jejunum -- drug effects
- Lipids -- blood
- Lipogenesis -- drug effects
- Liver -- drug effects
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Obese
- Nuclear Proteins -- genetics
- Obesity -- genetics
- Oxidative Stress -- drug effects
- Pentoxifylline -- pharmacology
- Sodium-Glucose Transporter 1 -- genetics
- Sterol Regulatory Element Binding Protein 1 -- genetics
- Transaminases -- blood
- Transcription Factors -- genetics
- Triglycerides -- blood
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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