The synthesis and biological evaluation of 2-amino-4,5,6,7,8,9-hexahydrocycloocta[b]thiophenes as allosteric modulators of the A1 adenosine receptor. [electronic resource]
Producer: 20111122Description: 3704-7 p. digitalISSN:- 1464-3405
- Allosteric Regulation -- drug effects
- Amines -- chemical synthesis
- Animals
- CHO Cells
- Cells, Cultured
- Cricetinae
- Cricetulus
- Cyclization -- drug effects
- Inhibitory Concentration 50
- Molecular Structure
- Receptor, Adenosine A1 -- metabolism
- Structure-Activity Relationship
- Thiophenes -- chemical synthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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