Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1. [electronic resource]
Producer: 20110913Description: e160 p. digitalISSN:- 2041-4889
- Apoptosis -- drug effects
- Ataxia Telangiectasia -- metabolism
- Breast Neoplasms -- genetics
- Cell Cycle Proteins -- genetics
- Cell Line, Tumor
- Checkpoint Kinase 1
- Colorectal Neoplasms -- genetics
- DNA Damage -- drug effects
- DNA Replication -- drug effects
- Female
- Furans -- pharmacology
- Gene Knockdown Techniques
- Histones -- genetics
- Humans
- Hypoxia -- genetics
- Hypoxia-Inducible Factor 1, alpha Subunit -- antagonists & inhibitors
- Osteosarcoma -- genetics
- Phosphorylation -- drug effects
- Protein Kinase Inhibitors -- pharmacology
- Protein Kinases -- biosynthesis
- Replication Origin -- drug effects
- S Phase -- drug effects
- Signal Transduction -- drug effects
- Transfection
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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