Rapamycin partially mimics the anticancer effects of calorie restriction in a murine model of pancreatic cancer. [electronic resource]
Producer: 20111115Description: 1041-51 p. digitalISSN:- 1940-6215
- Animals
- Antibiotics, Antineoplastic -- therapeutic use
- Blotting, Western
- Body Weight -- drug effects
- Caloric Restriction
- Carcinoma, Pancreatic Ductal -- metabolism
- Combined Modality Therapy
- Disease Models, Animal
- Glucose -- metabolism
- Glucose Tolerance Test
- Glycogen Synthase Kinase 3 -- metabolism
- Glycogen Synthase Kinase 3 beta
- Immunoenzyme Techniques
- Insulin-Like Growth Factor I -- metabolism
- Male
- Mice
- Mice, Inbred C57BL
- Mitogen-Activated Protein Kinases -- metabolism
- Pancreatic Neoplasms -- metabolism
- Phosphorylation -- drug effects
- Proto-Oncogene Proteins c-akt -- metabolism
- Ribosomal Protein S6 Kinases, 70-kDa -- metabolism
- STAT3 Transcription Factor -- metabolism
- Sirolimus -- therapeutic use
- TOR Serine-Threonine Kinases -- metabolism
- Tumor Cells, Cultured
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural
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