B7-H3 silencing increases paclitaxel sensitivity by abrogating Jak2/Stat3 phosphorylation. [electronic resource]
Producer: 20111109Description: 960-71 p. digitalISSN:- 1538-8514
- Animals
- Antigens, CD -- biosynthesis
- Antineoplastic Agents, Phytogenic -- pharmacology
- Apoptosis -- drug effects
- B7 Antigens
- Breast Neoplasms -- genetics
- Cell Line
- Cell Line, Tumor
- Drug Resistance, Neoplasm
- Female
- Humans
- Inhibitor of Apoptosis Proteins -- genetics
- Janus Kinase 2 -- metabolism
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Myeloid Cell Leukemia Sequence 1 Protein
- Paclitaxel -- pharmacology
- Phosphorylation -- drug effects
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- RNA, Small Interfering -- administration & dosage
- Receptors, Immunologic -- biosynthesis
- STAT3 Transcription Factor -- metabolism
- Survivin
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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