B7-H3 silencing increases paclitaxel sensitivity by abrogating Jak2/Stat3 phosphorylation.

Liu, Hao

B7-H3 silencing increases paclitaxel sensitivity by abrogating Jak2/Stat3 phosphorylation. [electronic resource] - Molecular cancer therapeutics Jun 2011 - 960-71 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1538-8514

10.1158/1535-7163.MCT-11-0072 doi


Animals
Antigens, CD--biosynthesis
Antineoplastic Agents, Phytogenic--pharmacology
Apoptosis--drug effects
B7 Antigens
Breast Neoplasms--genetics
Cell Line
Cell Line, Tumor
Drug Resistance, Neoplasm
Female
Humans
Inhibitor of Apoptosis Proteins--genetics
Janus Kinase 2--metabolism
Mice
Mice, Inbred BALB C
Mice, Nude
Myeloid Cell Leukemia Sequence 1 Protein
Paclitaxel--pharmacology
Phosphorylation--drug effects
Proto-Oncogene Proteins c-bcl-2--genetics
RNA, Small Interfering--administration & dosage
Receptors, Immunologic--biosynthesis
STAT3 Transcription Factor--metabolism
Survivin