ER-α agonist induces conversion of fibroblasts into myofibroblasts, while ER-β agonist increases ECM production and wound tensile strength of healing skin wounds in ovariectomised rats. [electronic resource]
Producer: 20120116Description: 703-8 p. digitalISSN:- 1600-0625
- Animals
- Cell Differentiation -- drug effects
- Cells, Cultured
- Estrogen Receptor alpha -- agonists
- Estrogen Receptor beta -- agonists
- Extracellular Matrix -- drug effects
- Female
- Fibroblasts -- cytology
- Human Umbilical Vein Endothelial Cells
- Humans
- In Vitro Techniques
- Myofibroblasts -- cytology
- Nitriles -- pharmacology
- Ovariectomy
- Phenols -- pharmacology
- Pyrazoles -- pharmacology
- Rats
- Rats, Sprague-Dawley
- Selective Estrogen Receptor Modulators -- pharmacology
- Skin -- drug effects
- Tensile Strength -- drug effects
- Wound Healing -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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