In vitro and in vivo evaluation of [18F]-FDEGPECO as a PET tracer for imaging the metabotropic glutamate receptor subtype 5 (mGluR5). [electronic resource]
Producer: 20110725Description: 984-91 p. digitalISSN:- 1095-9572
- Animals
- Autoradiography
- Biotransformation
- Blood-Brain Barrier -- physiology
- Brain -- anatomy & histology
- Brain Chemistry
- Cell Line
- Cell Membrane Permeability
- Fluorine Radioisotopes
- Humans
- Image Processing, Computer-Assisted
- In Vitro Techniques
- Isotope Labeling
- Male
- Microsomes, Liver -- metabolism
- Oximes -- chemical synthesis
- Positron-Emission Tomography -- methods
- Pyridines -- chemical synthesis
- Radiopharmaceuticals -- chemical synthesis
- Rats
- Rats, Sprague-Dawley
- Receptor, Metabotropic Glutamate 5
- Receptors, Metabotropic Glutamate -- metabolism
- Tissue Distribution
- Whole Body Imaging
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Publication Type: Journal Article
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