Electron density guided fragment-based drug design--a lead generation example. [electronic resource]
Producer: 20110616Description: 487-508 p. digitalISSN:- 1557-7988
- Adenosine Triphosphate -- metabolism
- Adenylyl Imidodiphosphate -- metabolism
- Catalytic Domain -- drug effects
- Crystallography, X-Ray
- Drug Design
- Drug Discovery
- Drug Evaluation, Preclinical -- methods
- Electrons
- Enzyme Inhibitors -- chemistry
- Fructokinases -- antagonists & inhibitors
- Fructose -- metabolism
- Hydrogen Bonding
- Models, Molecular
- Protein Binding
- Small Molecule Libraries
- Sulfates -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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