From target selection to the minimum acceptable biological effect level for human study: use of mechanism-based PK/PD modeling to design safe and efficacious biologics. [electronic resource]
Producer: 20110826Description: 169-78 p. digitalISSN:- 1550-7416
- Animals
- Antibodies, Monoclonal -- administration & dosage
- Cytomegalovirus -- immunology
- Dose-Response Relationship, Drug
- Drug Delivery Systems
- Drug Design
- Feasibility Studies
- Glycoproteins -- immunology
- Humans
- Immunologic Factors -- administration & dosage
- Macaca fascicularis
- Models, Biological
- Species Specificity
- Translational Research, Biomedical -- methods
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Publication Type: Journal Article
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