Ethanesulfohydroxamic acid ester prodrugs of nonsteroidal anti-inflammatory drugs (NSAIDs): synthesis, nitric oxide and nitroxyl release, cyclooxygenase inhibition, anti-inflammatory, and ulcerogenicity index studies. [electronic resource]
Producer: 20110606Description: 1356-64 p. digitalISSN:- 1520-4804
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- adverse effects
- Carrageenan
- Cyclooxygenase Inhibitors -- adverse effects
- Edema -- chemically induced
- Esters
- Gastric Mucosa -- drug effects
- Humans
- Hydroxamic Acids -- adverse effects
- Ibuprofen -- adverse effects
- Indomethacin -- adverse effects
- Male
- Naproxen -- adverse effects
- Nitric Oxide Donors -- adverse effects
- Nitrogen Oxides -- metabolism
- Prodrugs -- adverse effects
- Rats
- Rats, Sprague-Dawley
- Stereoisomerism
- Stomach Ulcer -- chemically induced
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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