TNF-related apoptosis-inducing ligand cooperates with NSAIDs via activated Wnt signalling in (pre)malignant colon cells. [electronic resource]
Producer: 20110222Description: 378-89 p. digitalISSN:- 1096-9896
- Adenoma -- metabolism
- Adult
- Aged
- Anti-Inflammatory Agents, Non-Steroidal -- pharmacology
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Aspirin -- pharmacology
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors -- physiology
- Caco-2 Cells
- Colon -- drug effects
- Colonic Neoplasms -- metabolism
- Dose-Response Relationship, Drug
- Drug Evaluation, Preclinical -- methods
- Drug Synergism
- Female
- Humans
- Intestinal Mucosa -- drug effects
- Male
- Middle Aged
- Neoplasm Proteins -- metabolism
- Receptors, TNF-Related Apoptosis-Inducing Ligand -- metabolism
- Recombinant Proteins -- pharmacology
- Signal Transduction -- drug effects
- Sulindac -- pharmacology
- TNF-Related Apoptosis-Inducing Ligand -- pharmacology
- Transcription Factor 4
- Transcription Factors -- physiology
- Tumor Cells, Cultured
- Wnt Proteins -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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