TNF-related apoptosis-inducing ligand cooperates with NSAIDs via activated Wnt signalling in (pre)malignant colon cells.

Heijink, Dianne M

TNF-related apoptosis-inducing ligand cooperates with NSAIDs via activated Wnt signalling in (pre)malignant colon cells. [electronic resource] - The Journal of pathology Feb 2011 - 378-89 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1096-9896

10.1002/path.2797 doi


Adenoma--metabolism
Adult
Aged
Anti-Inflammatory Agents, Non-Steroidal--pharmacology
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Aspirin--pharmacology
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors--physiology
Caco-2 Cells
Colon--drug effects
Colonic Neoplasms--metabolism
Dose-Response Relationship, Drug
Drug Evaluation, Preclinical--methods
Drug Synergism
Female
Humans
Intestinal Mucosa--drug effects
Male
Middle Aged
Neoplasm Proteins--metabolism
Receptors, TNF-Related Apoptosis-Inducing Ligand--metabolism
Recombinant Proteins--pharmacology
Signal Transduction--drug effects
Sulindac--pharmacology
TNF-Related Apoptosis-Inducing Ligand--pharmacology
Transcription Factor 4
Transcription Factors--physiology
Tumor Cells, Cultured
Wnt Proteins--physiology