Chronic administration of ethanol leads to an increased incidence of hepatocellular adenoma by promoting H-ras-mutated cells. [electronic resource]
Producer: 20110228Description: 161-7 p. digitalISSN:- 1872-7980
- Adenoma, Liver Cell -- chemically induced
- Animals
- Cell Proliferation -- drug effects
- Central Nervous System Depressants -- administration & dosage
- DNA Damage
- Dose-Response Relationship, Drug
- Ethanol -- administration & dosage
- Gene Frequency
- Hepatitis, Alcoholic -- etiology
- Immunohistochemistry
- Liver -- drug effects
- Liver Neoplasms, Experimental -- chemically induced
- Male
- Mice
- Mice, Inbred Strains
- Mutagenesis -- drug effects
- Oxidative Stress -- drug effects
- Proliferating Cell Nuclear Antigen -- analysis
- Time Factors
- beta Catenin -- metabolism
- ras Proteins -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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