Development of sporadic microsatellite instability in colorectal tumors involves hypermethylation at methylated-in-tumor loci in adenoma. [electronic resource]
Producer: 20110321Description: 2347-56 p. digitalISSN:- 1525-2191
- Adaptor Proteins, Signal Transducing -- genetics
- Adenoma -- genetics
- Aged
- Aged, 80 and over
- Biological Assay -- methods
- Colorectal Neoplasms -- genetics
- DNA Methylation
- DNA Mismatch Repair
- DNA Mutational Analysis
- Disease Progression
- Female
- Humans
- Kaplan-Meier Estimate
- Male
- Microsatellite Instability
- MutL Protein Homolog 1
- Mutation
- Nuclear Proteins -- genetics
- Proto-Oncogene Proteins -- genetics
- Proto-Oncogene Proteins B-raf -- genetics
- Proto-Oncogene Proteins p21(ras)
- ras Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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