Development of sporadic microsatellite instability in colorectal tumors involves hypermethylation at methylated-in-tumor loci in adenoma.

de Maat, Michiel F G

Development of sporadic microsatellite instability in colorectal tumors involves hypermethylation at methylated-in-tumor loci in adenoma. [electronic resource] - The American journal of pathology Nov 2010 - 2347-56 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1525-2191

10.2353/ajpath.2010.091103 doi


Adaptor Proteins, Signal Transducing--genetics
Adenoma--genetics
Aged
Aged, 80 and over
Biological Assay--methods
Colorectal Neoplasms--genetics
DNA Methylation
DNA Mismatch Repair
DNA Mutational Analysis
Disease Progression
Female
Humans
Kaplan-Meier Estimate
Male
Microsatellite Instability
MutL Protein Homolog 1
Mutation
Nuclear Proteins--genetics
Proto-Oncogene Proteins--genetics
Proto-Oncogene Proteins B-raf--genetics
Proto-Oncogene Proteins p21(ras)
ras Proteins--genetics