Nanaomycin A selectively inhibits DNMT3B and reactivates silenced tumor suppressor genes in human cancer cells. [electronic resource]
Producer: 20110228Description: 3015-23 p. digitalISSN:- 1538-8514
- Antineoplastic Agents -- pharmacology
- DNA (Cytosine-5-)-Methyltransferases -- antagonists & inhibitors
- DNA Methylation -- drug effects
- Drug Evaluation, Preclinical
- Enzyme Inhibitors -- pharmacology
- Gene Expression Regulation, Neoplastic -- drug effects
- Gene Silencing -- drug effects
- Genes, Tumor Suppressor -- drug effects
- HCT116 Cells
- HL-60 Cells
- HeLa Cells
- Humans
- Inhibitory Concentration 50
- Models, Biological
- Naphthoquinones -- pharmacology
- Neoplasms -- genetics
- Substrate Specificity
- Transcriptional Activation -- drug effects
- Tumor Cells, Cultured
- DNA Methyltransferase 3B
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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